Klemens Rottner Selected Research

Melanoma (Melanoma, Malignant)

10/2023	Ena/VASP clustering at microspike tips involves lamellipodin but not I-BAR proteins, and absolutely requires unconventional myosin-X.
1/2019	Functional integrity of the contractile actin cortex is safeguarded by multiple Diaphanous-related formins.
11/2018	On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility.
1/2017	FMNL formins boost lamellipodial force generation.
1/2009	F- and G-actin concentrations in lamellipodia of moving cells.

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Klemens Rottner Research Topics

Disease

10	Cicatrix (Scar) 01/2020 - 10/2002
8	Infections 06/2024 - 06/2003
7	Neoplasms (Cancer) 12/2022 - 06/2008
5	Melanoma (Melanoma, Malignant) 10/2023 - 01/2009
2	Stomach Neoplasms (Stomach Cancer) 06/2024 - 06/2021
2	Blister (Bulla) 10/2019 - 01/2019
1	Helicobacter Infections 06/2024
1	Herpes Zoster 06/2024
1	Synucleinopathies 04/2024
1	Parkinson Disease (Parkinson's Disease) 04/2024
1	Vascular Diseases (Vascular Disease) 12/2023
1	Retinal Neovascularization 12/2023
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2023
1	Sepsis (Septicemia) 04/2022
1	Lung Injury 04/2022
1	Adenocarcinoma 08/2021
1	Inflammation (Inflammations) 12/2020
1	Multiple Sclerosis 12/2020
1	Neuroinflammatory Diseases 12/2020
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 12/2020
1	Demyelinating Diseases (Demyelinating Disease) 12/2020
1	Pancreatic Neoplasms (Pancreatic Cancer) 11/2019
1	Neoplasm Metastasis (Metastasis) 11/2019
1	Pemphigus (Pemphigus Vulgaris) 01/2019
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2019
1	Leukemia 01/2019
1	Autoimmune Diseases (Autoimmune Disease) 01/2019
1	Fibrosis (Cirrhosis) 01/2018
1	Ovarian Neoplasms (Ovarian Cancer) 04/2016
1	Bone Resorption 01/2014
1	Tetraploidy 08/2013
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2013
1	Wiskott-Aldrich Syndrome 11/2010
1	Glioblastoma (Glioblastoma Multiforme) 05/2006
1	autosomal recessive 1 Spinocerebellar ataxia 06/2003

Drug/Important Bio-Agent (IBA)

12	CortactinIBA 06/2024 - 07/2009
8	Actin-Related Protein 2-3 Complex (Arp2 3 Complex)IBA 01/2020 - 10/2002
7	Proteins (Proteins, Gene)FDA Link 10/2023 - 10/2002
5	Microfilament Proteins (Actin Binding Proteins)IBA 06/2024 - 01/2019
3	Tyrosine (L-Tyrosine)FDA Link 12/2023 - 06/2021
3	Wiskott-Aldrich Syndrome Protein FamilyIBA 01/2020 - 10/2002
3	ForminsIBA 01/2019 - 01/2017
3	Wiskott-Aldrich Syndrome ProteinIBA 11/2013 - 10/2002
2	CarcinogensIBA 06/2024 - 08/2021
2	Phosphotransferases (Kinase)IBA 06/2021 - 01/2020
2	Protein Isoforms (Isoforms)IBA 01/2020 - 10/2019
2	Actins (F Actin)IBA 11/2018 - 01/2009
2	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 01/2018 - 02/2004
2	Cyclic AMP Receptors (Cyclic AMP Receptor)IBA 09/2013 - 06/2006
1	Tight Junction ProteinsIBA 06/2024
1	Oncogene Proteins (Oncogene Protein)IBA 06/2024
1	SynucleinsIBA 04/2024
1	Oxygen (Dioxygen)IBA 12/2023
1	Small Interfering RNA (siRNA)IBA 12/2023
1	Chemokine ReceptorsIBA 01/2023
1	Fenofibrate (CiL)FDA LinkGeneric 01/2022
1	Cell Adhesion MoleculesIBA 01/2022
1	src-Family KinasesIBA 08/2021
1	Biomarkers (Surrogate Marker)IBA 06/2021
1	CytokinesIBA 12/2020
1	Proline (L-Proline)FDA Link 01/2020
1	lysophosphatidic acidIBA 11/2019
1	AutoantibodiesIBA 01/2019
1	DesmogleinsIBA 01/2019
1	Peptides (Polypeptides)IBA 12/2017
1	myosin VIIBA 04/2016
1	Coat Protein Complex I (COPI)IBA 01/2016
1	Actin-Related Protein 2IBA 09/2013
1	PhosphatidylserinesIBA 08/2013
1	metavinculinIBA 01/2013
1	Octoxynol (Triton X 100)IBA 01/2009
1	SNARE Proteins (SNAREs)IBA 06/2008
1	Peptide Hydrolases (Proteases)FDA Link 06/2008
1	Matrix Metalloproteinase 14 (MT1-MMP)IBA 06/2008
1	nucleic acid probe 1IBA 06/2006
1	rho-Associated KinasesIBA 05/2006
1	Multiprotein ComplexesIBA 02/2004

Therapy/Procedure

1	Therapeutics 12/2023
1	Heterologous Transplantation (Xenotransplantation) 01/2023
1	Ligation 04/2022
1	Punctures 04/2022
1	Traction 05/2006